Perchlorate Exposure and Dose Estimates in Infants

Developmental Perchlorate Exposure: Gilbert Responds

Effects of six months of daily low-dose perchlorate exposure on thyroid function in healthy volunteers.

CONTEXT Perchlorate has been detected in U.S. drinking water supplies at levels ranging from 4 to 200 microg/liter as well as in agricultural products. Perchlorate is known to be a competitive inhibitor of iodine uptake by the thyroid through the sodium-iodide symporter. OBJECTIVE The objective of the study was to determine whether prolonged exposure (6 months) to low levels of perchlorate wo...

Perchlorate Exposure and Thyroid Function in Ammonium Perchlorate Workers in Yicheng, China

The impact of low level dust on the thyroid function of workers chronically exposed to ammonium perchlorate (AP) is uncertain and controversial. The aim of this study was to examine whether workers in China with long-term (>3 years) occupational exposure to low levels of AP dust had affected thyroid homeostasis. Mean occupational exposures to AP dust ranged from 0.43 to 1.17 mg/m3. Geometric me...

Developmental Perchlorate Exposure and Synaptic Transmission in Hippocampus

Low-dose mercury exposure in early life: relevance of thimerosal to fetuses, newborns and infants.

This review explores the different aspects of constitutional factors in early life that modulate toxicokinetics and toxicodynamics of low-dose mercury resulting from acute ethylmercury (etHg) exposure in Thimerosal-containing vaccines (TCV). Major databases were searched for human and experimental studies that addressed issues related to early life exposure to TCV. It can be concluded that: a) ...